Todos recibieron combinaciones de antiepilépticos, siendo eficaces en el 36%. Durante el periodo de POCS, el 72% presentó alguna manifestación clínica añadida. La edad media al inicio de la POCS fue de 6,7 años, siendo menor en los casos secundarios. El 24% restante eran niños sanos o con epilepsias benignas (POCS primaria).

El 76% presentaba de base alteraciones en pruebas de neuroimagen o retraso psicomotor (POCS secundaria). Obtuvimos una muestra de 25 pacientes (68% varones). MétodosĮstudio observacional retrospectivo de pacientes pediátricos con POCS seguidos en un hospital terciario en el periodo de noviembre 1997 a noviembre 2017. El objetivo de nuestro estudio es analizar las características epidemiológicas y clínicas de pacientes que presentan en algún momento de su evolución POCS, describir la respuesta a distintos tratamientos y estudiar factores predictores de su evolución. Este patrón electroencefalográfico puede aparecer tanto en determinados síndromes epilépticos como en la evolución de epilepsias idiopáticas y sintomáticas. La punta-onda continua durante el sueño lento (POCS) es un trazado electroencefalográfico característico, que aparece en la infancia y que en ocasiones condiciona un deterioro cognitivo. A close follow-up of the patients with epilepsy is important, especially if associated with cognitive impairment, in order to establish an early diagnosis and treatment. The CSWS pattern, although rare, is still a therapeutic challenge. Outcome was poorer in those with secondary CSWS and, in those whose CSWS started at an earlier age and lasted longer. One-third (33%) presented with sequelae, mostly cognitive and behavioural alterations. CSWS stopped in 72%, and remission was longer if the CSWS onset occurred at an older age. All of them were treated with antiepileptic drugs, which were effective in 36%. Symptoms were present during the CSWS episode in 72% of cases. The mean age of onset of CSWS was 6.7 years, but earlier in the secondary CSWS cases. The rest were healthy, or diagnosed with idiopathic epilepsy. The study included 25 patients (68% male), of whom 76% had abnormalities in the neuroimaging or suffered from psychomotor development disorder (secondary CSWS). MethodsĪ retrospective study was conducted on paediatric patients with CSWS treated in a third-level hospital from November 1997 to November 2017. The aim of this study is to analyse epidemiological and clinical characteristics of patients with CSWS, in order to describe possible predictive factors in their outcome. It can appear in the course of epileptic syndromes, as well as in benign epilepsy. Continuous spikes and waves during slow sleep (CSWS) is an EEG pattern that appears during childhood, and is often associated with cognitive impairment.

Xl spike definition